Advice on the safe introduction and continued use of isotretinoin in acne in the U.K. 2010.

نویسندگان

  • M J D Goodfield
  • N H Cox
  • A Bowser
  • J C McMillan
  • L G Millard
  • N B Simpson
  • A D Ormerod
چکیده

Department of Dermatology, Leeds General Infirmary, Leeds LS1 3EX, U.K. *Department of Dermatology, Cumberland Infirmary, Carlisle CA2 7HY, U.K. Independent Acne Patient Advisor, Belfast City Hospital, Belfast BT9 7AB, U.K. Department of Dermatology, Belfast City Hospital, Belfast BT9 7AB, U.K. §Department of Dermatology, The Park Hospital, Arnold, Nottingham NG5 5BX, U.K. –Department of Dermatology, Nuffield Health Newcastle upon Tyne Hospital, Newcastle upon Tyne NE2 1JP, U.K. **Department of Dermatology, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZN, U.K.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

بررسی اثر ایزوترتینویین بر سطح سرمی آنزیم کراتین فسفوکیناز و علایم عضلانی- اسکلتی در بیماران مبتلا به آکنه ولگاریس

Background: Acne vulgaris is a common dermatologic disease. Isotretinoin is one of the medications prescribed in severe cases of acne. Despite its high efficacy, isotretinoin use for acne is associated with some side effects. This study was done to evaluate the effects of isotretinoin on serum levels of creatine phosphokinase (CPK) and musculoskeletal symptoms in patients with acne vulgaris. M...

متن کامل

Evaluation of the efficacy of intermittent Isotretinoin doses in Acne patients

Background and objective: Oral isotretinoin is the only treatment that has an effect on all the major etiological factors involved in acne (Increased sebum production, alterations in microbial flora, hyperkeratinization of pilosebaceous duct, and inflammation). Considering complications and relative expense, several treatment regimens have been suggested. The objective of this study was to eval...

متن کامل

The effect of metformin in the treatment of intractable and late onset acne: a comparison with oral isotretinoin

Background: Insulin resistance and increased insulin-like growth factor (IGF)-1 with consequent mammalian target of rapamycin complex (mTORC) 1 overexpression is responsible for acne pathogenesis, especially in women with polycystic ovary syndrome (PCOS). Metformin is shown to improve acne as an adjunct therapy in females with PCOS and males with altered metabolic profile. We evaluated the use ...

متن کامل

بررسی اثر ایزوترتینوئین خوراکی بر سطح فولات سرم

Acne vulgaris is one of the most common skin disorders and Isotretinoin has widely been used as a treatment for its severe and resistant cases in recent years. Considering the controversy over the effect of systemic Isotretinoin on reducing the plasma level of folic acid and the negative effect of this reduction on health, this study was conducted to assess the influence of systemic Isotretinoi...

متن کامل

Effects of Isotretinoin on bone density and Calcium homeostasis in patients with Acne Vulgaris

Background and aim: Side effects of long-term systemic isotretinion use with high accumulative doses on skeletal system have been known, but there are few studies about the effects of short term isotretinoin therapy for acne patients. This study was aimed to recognize the effects of systemic isotretinion on calcium homeostasis and bone density in acne patients referring to clinics affilia...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The British journal of dermatology

دوره 162 6  شماره 

صفحات  -

تاریخ انتشار 2010